What is the primary clinical use of Cefotetan?

Cefotetan is primarily used for the treatment of anaerobic infections. It belongs to the cephalosporin class of antibiotics and is particularly effective against anaerobic bacteria such as Bacteroides fragilis and Clostridium species. These types of bacteria are often involved in intra-abdominal infections, pelvic infections, and other conditions where anaerobes may be present. The unique structural properties of cefotetan allow for reliable penetration and action against anaerobic organisms, which are less accessible to many other antibiotics.

While cefotetan can be used for prophylaxis in certain surgical settings due to its anaerobic coverage, it is not the preferred choice for all surgical types, especially orthopedic procedures. Furthermore, while it can have activity against some gram-negative infections, this is not its primary indication compared to its efficacy in anaerobic infections. Its role in respiratory infections is limited as well, as other antibiotics may be more efficient for treating the wide range of pathogens involved in respiratory infections. This highlights the specific clinical scenarios where cefotetan is most beneficial and underscores its designation as an effective treatment for anaerobic infections.