Which antibiotic is contraindicated in children under 8 years of age?

Tetracyclines are contraindicated in children under 8 years of age due to their potential to cause permanent tooth discoloration and affect bone development. This class of antibiotics can bind to calcium in developing teeth and bones, leading to intrinsic staining of the teeth and inhibiting proper growth.

In contrast, while clindamycin and chloramphenicol can have their own sets of concerns, they do not have the same age-related contraindications as tetracyclines. Linezolid, although used carefully in pediatrics, is not associated with the same specific risks for children under 8 as tetracyclines. Therefore, tetracyclines are consistently advised against in this age group to prevent long-term dental and skeletal issues.